Hi all, Can anyone help, the Methotrexate I'm taking is constantly making me nauseous, and having spoken to the IDB Nurse, I'm told there is another aternative, although she didn't say what (she did not have any knowledge on injecting it so it would seem it wouldn't be that).  It can't be azathioprine either because I've tried that and could not tolerate it.  So does anyone else know what is next?  I'm also on infliximab, but have another Fistula worming it's nasty way through, so it would appear that neither of the drugs are working (pretty  much confirmed by the IBD Nurse).  I would be welcome any ideas as they have now brought my September appointment forward to next week, so if there are any suggestions I could do some homework before I get there. Thanks All in advance